Human cells produce VOCs as by-products of metabolic activities and inflammation. The release of specific variants and concentrations of metabolites like VOCs directly reflects the state of metabolic function; facilitating monitoring of glucose levels, as well as signalling underlying physiological conditions; such as sepsis.
These VOCs are very small molecules that interact with blood plasma and diffuse into the bloodstream for circulation around the body.
Once reaching the lungs they cross the blood-air barrier at the alveolar membranes before being released from the alveoli into exhaled breath, allowing non-invasive sampling.
Metabolites like VOCs are by-products of metabolic activities and inflammation.
Entering the bloodstream VOCs circulate around the body.
At the lungs VOCs cross the blood-air barrier.
These insight-bearing VOCs are released in exhaled breath allowing non-invasive sampling.
Our proprietary technology enables active health and disease monitoring.
BOYDSense have developed proprietary MOx sensors of high accuracy and reliability in identifying and measuring the concentrations of specific metabolites like VOCs. Our advancements in technological development and manufacturing techniques allow cost-effective production and miniaturisation enabling compact and portable devices.
On-board analysis algorithms deliver direct results, whether operating as a stand-alone device, or connected with the Cloud - sharing data as part of a connected healthcare solution.
Our first application will be in diabetes but our technology has potential for many other applications, offering a rich sampling matrix for chronic disease monitoring and health assessment.
Our roadmap for development spans health considerations, technology platforms and extends from disease monitoring to management solutions.
MOx sensors response in measuring specific VOC metabolites
The MOx sensor is first analyzing the exogeneous VOCs from ambient air until the breath sample is introduced (sample ON). The Mox sensor is then reacting to the endogenous VOCs (metabolites) until the breath sample is wiped out. BOYDSense proprietary MOx sensor array allows measuring specific VOC metabolites to deliver chronic condition monitoring based on on-board algorithms.
Reference: BOYDSense R&D
Literature reviews revealed the initial possibilities of this technology. Our continued efforts and development have resulted in a sequence of clinical studies, further expanding our knowledge, expertise and capabilities.
Our latest clinical investigations continue to move our technology and devices toward market launch.
BOYDSense continue to present our clinical results at prestigious international congresses, keeping our scientific peers informed of our ongoing progress.
Craig Cooper, Investment Director of the Swiss Diabetes Venture Fund
William H. Polonsky, PhD, CDE, President, The Behavioral Diabetes Institute
Prof. Dr. Lutz Heinemann, Science Consulting in Diabetes GmbH, Düsseldorf, Germany
Derek Brandt, CEO Diabetes Center Berne.