Our Story

We breathe in and out around 22,000 times a day.
Each time we exhale our breath is revealing clues to our health, wellbeing and the status of chronic conditions.

At BOYDSense we are unlocking the power of breath.

During exhalation, metabolites such as Volatile Organic Compounds (VOCs) are released in the breath. The presence and concentration of specific metabolites like VOCs in each exhaled breath reflects the status of metabolic and health conditions, providing invaluable diagnostic information.

Human cells produce VOCs as by-products of metabolic activities and inflammation. The release of specific variants and concentrations of metabolites like VOCs directly reflects the state of metabolic function; facilitating monitoring of glucose levels, as well as signalling underlying physiological conditions; such as sepsis.

These VOCs are very small molecules that interact with blood plasma and diffuse into the bloodstream for circulation around the body.

Once reaching the lungs they cross the blood-air barrier at the alveolar membranes before being released from the alveoli into exhaled breath, allowing non-invasive sampling.

Image showing Metabolites floating in a blood vessel alongside Hemoglobin cells

The Process

Icon showing cell shapes representing metabolites

Metabolites like VOCs are by-products of metabolic activities and inflammation.

Icon showing two arrows around a heart representing VOCs entering the bloodstream

Entering the bloodstream VOCs circulate around the body.

Icon showing arrows moving up out of the lungs into the air

At the lungs VOCs cross the blood-air barrier.

Icon showing arrows leading to a molecular structure representing exhalation of breath and detectable molecules

These insight-bearing VOCs are released in exhaled breath allowing non-invasive sampling.

Icon showing an computer screen with a magnifying glass hovering over a graph

Our proprietary technology enables active health and disease monitoring.

Our Technology

The BOYDSense team have more than 25 years experience developing sensor arrays and algorithms that meet the accuracy and accountability demanded by medical applications.

Our technology development pipeline is empowered by advanced proprietary sensor and breath sampling modules, enabled by pioneering algorithms specifically developed for diagnosis and biomedical solutions.

BOYDSense have developed proprietary MOx sensors of high accuracy and reliability in identifying and measuring the concentrations of specific metabolites like VOCs. Our advancements in technological development and manufacturing techniques allow cost-effective production and miniaturisation enabling compact and portable devices.

On-board analysis algorithms deliver direct results, whether operating as a stand-alone device, or connected with the Cloud - sharing data as part of a connected healthcare solution.

Our first application will be in diabetes but our technology has potential for many other applications, offering a rich sampling matrix for chronic disease monitoring and health assessment.

Our roadmap for development spans health considerations, technology platforms and extends from disease monitoring to management solutions.

MOx sensors response in measuring specific VOC metabolites

Graph showing MOx curves data

The MOx sensor is first analyzing the exogeneous VOCs from ambient air until the breath sample is introduced (sample ON). The Mox sensor is then reacting to the endogenous VOCs (metabolites) until the breath sample is wiped out. BOYDSense proprietary MOx sensor array allows measuring specific VOC metabolites to deliver chronic condition monitoring based on on-board algorithms.
Reference: BOYDSense R&D

Based on Clinical Studies and Congress Contributions

BOYDSense believe in the power of science.
Science is the foundation of our development and technology.

Literature reviews revealed the initial possibilities of this technology. Our continued efforts and development have resulted in a sequence of clinical studies, further expanding our knowledge, expertise and capabilities.

Our latest clinical investigations continue to move our technology and devices toward market launch.

Development of a breath-based glucose estimation algorithm, a progress report.

Frank Flacke PhD et al.

Publication Pending

DTM 2024

Performance data of the first algorithm developed for the BOYDSense breath-based glucose estimation device.

Pierre Gourdy et al.

Diabetologia 67 (Suppl 1), 1–593 (2024)

EASD 2024

Detailed performance data of the first algorithm developed for the BOYDSense breath-based glucose estimation device.

P. Gourdy et al.

European Association for the Study of Diabetes

ATTD 2024

Developing a Breath-Based Glucose Estimation Device for People with Type 2 Diabetes.

P. Gourdy et al.

American Diabetes Association (June 2024)

ADA 2024

Development of a breath-based glucose estimation algorithm.

Frank Flacke PhD et al.

Journal of Diabetes Science and Technology (February 2024)

DTM 2023

BOYDSense continue to present our clinical results at prestigious international congresses, keeping our scientific peers informed of our ongoing progress.

Proudly invited to deliver oral presentations at
DTM 2023, ATTD 2024

"We see huge potential for breath glucose monitoring and BOYDSense is one of the leading companies in this space."

Craig Cooper, Investment Director of the Swiss Diabetes Venture Fund

"New approaches to glucose monitoring, such as the BOYDSense technology, have the potential to make quite a positive impact on the long-term management of diabetes."

William H. Polonsky, PhD, CDE, President, The Behavioral Diabetes Institute

"There is clear need for an easy to perform, easily accessible and rapid measurement of glucose levels in human beings. The analysis of breath offers such a monitoring option."

Prof. Dr. Lutz Heinemann, Science Consulting in Diabetes GmbH, Düsseldorf, Germany

"Worldwide we see currently around 600m People with Diabetes and only 12 million use CGM systems. So there is a significant opportunity for easy-to-use and non-invasive systems, such as BOYDSense applications, to fundamentally impact long-term outcomes."

Derek Brandt, CEO Diabetes Center Berne.